Prohibits a qualified entity that operates a syringe exchange program (program) from establishing or operating a fixed site for the distribution or exchange of a syringe or needle within 1,000 feet of specified facilities. Creates an exception. Allows the Indiana department of health to deny, suspend, or revoke a qualified entity's annual registration for a violation. Amends the duties of a qualified entity that operates a program. Establishes requirements for program participation. Prohibits a qualified entity that operates a program from providing chemical reagents or precursors. Requires the state health commissioner to investigate any complaint regarding a qualified entity's noncompliance with the qualified entity's duties concerning the operation of a program. Permits the state health commissioner to suspend or terminate the approval of a qualified entity for noncompliance. Extends the expiration of the program to July 1, 2031.