The bill requires enhanced reporting on drug manufacturing amounts and the inclusion of original manufacturer and supply chain information on drug labels. The Act amends the Federal Food, Drug, and Cosmetic Act to mandate additional information on the suppliers of drug ingredients and the respective amounts of drugs manufactured using those ingredients. There will be a more frequent reporting schedule, but no more than 4 times per year. Furthermore, drug labeling must include the name, place of business, and unique facility identifier of the original manufacturer of the drug and its ingredients, with some flexibility provided by the Secretary of Health and Human Services.